高龄(80岁以上)患者未破裂颅内动脉瘤的自然史与治疗对策
Unrupturedintracranialaneurysmsinpatientsover80years:naturalhistoryandmanagementimplications
目的:由于预期寿命缩短和治疗风险增加,确诊时年龄超过80岁的未破裂颅内动脉瘤(UIA)患者的治疗决策面临着独特的挑战。因此,我们调查研究了一个连续系列的80岁以后确诊的UIA患者的破裂风险与生存状况。
PurposePatientsovertheageof80yearswhendiagnosedwithanunrupturedintracranialaneurysm(UIA)poseuniquedecision-makingchallengesduetoshortenedlife-expectancyandincreasedriskoftreatment.Thus,weinvestigatedtheriskofruptureandsurvivalofaconsecutiveseriesofpatientswhowerediagnosedwithanUIAaftertheageof80years.
方法:评价连续性的UIA患者的数据,将首诊年龄在80-90岁之间的、经资深医师确诊的UIA患者纳入该研究。研究结局为确诊后动脉瘤破裂和总体生存状况。采用Kaplan-Meier生存曲线估算生存状况。与同期经资深医师确诊的、年龄低于65岁的患者人群进行危险因素发生率的比较。
MethodsDataofconsecutivepatientswithanUIAwerereviewed,andpatientswereincludedinourstudyiftheywerefirstevaluatedforaUIAbytheseniorauthorduringtheirninthdecadeoflife.Out